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Design of multi-epitope peptides containing HLA class-I and class-II-restricted epitopes derived from immunogenic Leishmania proteins, and evaluation of CD4+ and CD8+ T cell responses induced in cured cutaneous leishmaniasis subjects

Human leishmaniasis is a public health problem worldwide for which the development of a vaccine remains a challenge. T cell-mediated immune responses are crucial for protection. Peptide vaccines based on the identification of immunodominant T cell epitopes able to induce T cell specific immune respo...

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Detalles Bibliográficos
Autores principales:	Hamrouni, Sarra, Bras-Gonçalves, Rachel, Kidar, Abdelhamid, Aoun, Karim, Chamakh-Ayari, Rym, Petitdidier, Elodie, Messaoudi, Yasmine, Pagniez, Julie, Lemesre, Jean-Loup, Meddeb-Garnaoui, Amel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098648/ https://www.ncbi.nlm.nih.gov/pubmed/32176691 http://dx.doi.org/10.1371/journal.pntd.0008093

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