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Non-replicating Vaccinia Virus TianTan Strain (NTV) Translation Arrest of Viral Late Protein Synthesis Associated With Anti-viral Host Factor SAMD9

NTV is a highly attenuated virus that was created by genetically deleting 26 genes related to host range and virulence from TianTan strain. Since NTV is highly attenuated, it has been used widely as an optimizing viral vector. In this study, we explored the biological characteristics in vitro and th...

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Detalles Bibliográficos
Autores principales: Zhao, Ying, Zhao, Li, Huang, Panpan, Ren, Jiao, Zhang, Peng, Tian, Houwen, Tan, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098914/
https://www.ncbi.nlm.nih.gov/pubmed/32266167
http://dx.doi.org/10.3389/fcimb.2020.00116

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