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Pharmacophore-Based Virtual Screening Toward the Discovery of Novel Anti-echinococcal Compounds

Echinococcosis is a serious helminthic zoonosis with a great impact on human health and livestock husbandry. However, the clinically used drugs (benzimidazoles) have a low cure rate, so alternative drugs are urgently needed. Currently, drug screenings for echinococcosis are mainly phenotype-based, a...

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Detalles Bibliográficos
Autores principales: Liu, Congshan, Yin, Jianhai, Yao, Jiaqing, Xu, Zhijian, Tao, Yi, Zhang, Haobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098963/
https://www.ncbi.nlm.nih.gov/pubmed/32266168
http://dx.doi.org/10.3389/fcimb.2020.00118