Association of immunophenotype with expression of topoisomerase II α and β in adult acute myeloid leukemia

Anthracyclines used in the treatment of acute myelogenous leukemia (AML) inhibit the activity of the mammalian topoisomerase II (topo II) isoforms, topo II α and topo IIβ. In 230 patients with non-M3 AML who received frontline ara-C/daunorubicin we determined expression of topo IIα and topo IIβ by R...

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Detalles Bibliográficos
Autores principales: Michelson, Andrew P., McDonough, Shannon, Willman, Cheryl L., Koegle, Eric R., Godwin, John E., Petersdorf, Stephen H., List, Alan F., Othus, Megan, Appelbaum, Frederick R., Radich, Jerald P., Ganapathi, Mahrukh K., Advani, Anjali S., Ganapathi, Ram N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099013/
https://www.ncbi.nlm.nih.gov/pubmed/32218491
http://dx.doi.org/10.1038/s41598-020-62345-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099013/
https://www.ncbi.nlm.nih.gov/pubmed/32218491
http://dx.doi.org/10.1038/s41598-020-62345-9

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