Muscone Ameliorates Ovariectomy-Induced Bone Loss and Receptor Activator of Nuclear Factor-κb Ligand-Induced Osteoclastogenesis by Suppressing TNF Receptor–Associated Factor 6-Mediated Signaling Pathways

Postmenopausal osteoporosis is caused by the deficiency of estrogen, which breaks bone homeostasis and induces levels of pro-inflammatory cytokines. Muscone is a potent anti-inflammatory agent and is used to treat bone fracture in traditional Chinese medicine. However, its anti-osteoclastogenic effe...

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Detalles Bibliográficos
Autores principales: Zhai, Xiao, Yan, Zijun, Zhao, Jian, Chen, Kai, Yang, Yilin, Cai, Mengxi, He, Chen, Huang, Chunyou, Li, Bo, Yang, Mingyuan, Zhou, Xiaoyi, Zhao, Yingchuan, Wei, Xiaozhao, Bai, Yushu, Li, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099619/
https://www.ncbi.nlm.nih.gov/pubmed/32265718
http://dx.doi.org/10.3389/fphar.2020.00348

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