Cargando…

Exploration of thiaheterocyclic hHDAC6 inhibitors as potential antiplasmodial agents

AIM: The recurring resistance of the malaria parasite to many drugs compels the design of innovative chemical entities in antimalarial research. Pan-histone deacetylase inhibitors (pan-HDACis) have recently been presented in the literature as powerful novel antimalarials, although their application...

Descripción completa

Detalles Bibliográficos
Autores principales: Vreese, Rob De, de Kock, Carmen, Smith, Peter J, Chibale, Kelly, D'hooghe, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099625/
https://www.ncbi.nlm.nih.gov/pubmed/28263085
http://dx.doi.org/10.4155/fmc-2016-0215