Design, synthesis, heme binding and density functional theory studies of isoindoline-dione-4-aminoquinolines as potential antiplasmodials

AIM: WHO Malaria report 2017 estimated 216 million cases of malaria and 445,000 deaths worldwide, with 91% of deaths affecting the African region. RESULTS/METHODOLOGY: Microwave promoted the synthesis of cycloalkyl amine substituted isoindoline-1,3-dione-4-aminoquinolines was urbanized for evaluatin...

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Detalles Bibliográficos
Autores principales: Rani, Anu, Kumar, Sumit, Legac, Jenny, Adeniyi, Adebayo A, Awolade, Paul, Singh, Parvesh, Rosenthal, Philip J, Kumar, Vipan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Newlands Press Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099627/
https://www.ncbi.nlm.nih.gov/pubmed/31802710
http://dx.doi.org/10.4155/fmc-2019-0260

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