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The effect of SNPs in CYP450 in chloroquine/primaquine Plasmodium vivax malaria treatment

BACKGROUND: Chloroquine/primaquine is the current therapy to eliminate Plasmodium vivax infection in the Amazon region. AIMS: This study investigates CYP1A2, CYP2C8, CYP2C9, CYP3A4 and CYP3A5 genetic polymorphisms influence on cloroquine/primaquine treatment. PATIENTS & METHODS: Generalized esti...

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Detalles Bibliográficos
Autores principales:	Sortica, Vinicius A, Lindenau, Juliana D, Cunha, Maristela G, Ohnishi, Maria DO, Ventura, Ana Maria R, Ribeiro-dos-Santos, Ândrea KC, Santos, Sidney EB, Guimarães, Luciano SP, Hutz, Mara H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Future Medicine Ltd 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099632/ https://www.ncbi.nlm.nih.gov/pubmed/27767381 http://dx.doi.org/10.2217/pgs-2016-0131

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