Paroxysmal Discharges in Tissue Slices From Pediatric Epilepsy Surgery Patients: Critical Role of GABA(B) Receptors in the Generation of Ictal Activity

In the present study, we characterized the effects of bath application of the proconvulsant drug 4-aminopyridine (4-AP) alone or in combination with GABA(A) and/or GABA(B) receptor antagonists, in cortical dysplasia (CD type I and CD type IIa/b), tuberous sclerosis complex (TSC), and non-CD cortical...

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Detalles Bibliográficos
Autores principales: Levinson, Simon, Tran, Conny H., Barry, Joshua, Viker, Brett, Levine, Michael S., Vinters, Harry V., Mathern, Gary W., Cepeda, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099654/
https://www.ncbi.nlm.nih.gov/pubmed/32265658
http://dx.doi.org/10.3389/fncel.2020.00054

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