Cargando…

Respiratory viruses in patients and employees in an intensive care unit

PURPOSE: To evaluate the frequency of respiratory viruses in a nonselected population of intensive care unit patients and employees and to investigate the clinical as well as the epidemiological association with virological findings. METHODS: Between 12 January and 5 March 2009, nasopharyngeal swabs...

Descripción completa

Detalles Bibliográficos
Autores principales: Stupica, D., Lusa, L., Petrovec, M., Žigon, N., Jevšnik, M., Bogovič, P., Strle, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099890/
https://www.ncbi.nlm.nih.gov/pubmed/22350959
http://dx.doi.org/10.1007/s15010-012-0245-6
_version_ 1783511389437952000
author Stupica, D.
Lusa, L.
Petrovec, M.
Žigon, N.
Jevšnik, M.
Bogovič, P.
Strle, F.
author_facet Stupica, D.
Lusa, L.
Petrovec, M.
Žigon, N.
Jevšnik, M.
Bogovič, P.
Strle, F.
author_sort Stupica, D.
collection PubMed
description PURPOSE: To evaluate the frequency of respiratory viruses in a nonselected population of intensive care unit patients and employees and to investigate the clinical as well as the epidemiological association with virological findings. METHODS: Between 12 January and 5 March 2009, nasopharyngeal swabs were collected from 55 intensive care unit (ICU) patients and 41 medical personnel at 16 different time-points and tested for 11 respiratory viruses by single real-time PCR using TaqMan or MGB probes. RESULTS: Among the 55 ICU patients tested, there were 30 virus-positive respiratory specimens (30/173, 17.3%) and 23 patients who tested positive at least once for respiratory viruses (23/55, 41.8%). Only the time from admission to the ICU was associated with the probability of testing positive, with the probability of testing positive decreasing with increasing length of stay (P < 0.001). Of the 418 respiratory specimens collected from the healthcare personnel, 27 (6.5%) tested positive. Seventeen employees tested positive at least once for respiratory viruses (17/41, 41.5%). Among the employees, calendar time (P = 0.03) and having sick contacts at home (P = 0.006) were significantly associated with swab positivity. Among the study population, patients had a significantly higher probability of having a positive swab result than employees. The distribution of viruses differed between the two groups. CONCLUSIONS: Our results suggest that when hygiene precautions are adopted, the possibility of transmitting selected respiratory viruses between patients and personnel is limited. They also point to a greater importance of the community over the hospital environment for acquisition of viral respiratory infections by ICU patients and employees. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s15010-012-0245-6) contains supplementary material, which is available to authorized users.
format Online
Article
Text
id pubmed-7099890
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Springer-Verlag
record_format MEDLINE/PubMed
spelling pubmed-70998902020-03-27 Respiratory viruses in patients and employees in an intensive care unit Stupica, D. Lusa, L. Petrovec, M. Žigon, N. Jevšnik, M. Bogovič, P. Strle, F. Infection Clinical and Epidemiological Study PURPOSE: To evaluate the frequency of respiratory viruses in a nonselected population of intensive care unit patients and employees and to investigate the clinical as well as the epidemiological association with virological findings. METHODS: Between 12 January and 5 March 2009, nasopharyngeal swabs were collected from 55 intensive care unit (ICU) patients and 41 medical personnel at 16 different time-points and tested for 11 respiratory viruses by single real-time PCR using TaqMan or MGB probes. RESULTS: Among the 55 ICU patients tested, there were 30 virus-positive respiratory specimens (30/173, 17.3%) and 23 patients who tested positive at least once for respiratory viruses (23/55, 41.8%). Only the time from admission to the ICU was associated with the probability of testing positive, with the probability of testing positive decreasing with increasing length of stay (P < 0.001). Of the 418 respiratory specimens collected from the healthcare personnel, 27 (6.5%) tested positive. Seventeen employees tested positive at least once for respiratory viruses (17/41, 41.5%). Among the employees, calendar time (P = 0.03) and having sick contacts at home (P = 0.006) were significantly associated with swab positivity. Among the study population, patients had a significantly higher probability of having a positive swab result than employees. The distribution of viruses differed between the two groups. CONCLUSIONS: Our results suggest that when hygiene precautions are adopted, the possibility of transmitting selected respiratory viruses between patients and personnel is limited. They also point to a greater importance of the community over the hospital environment for acquisition of viral respiratory infections by ICU patients and employees. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s15010-012-0245-6) contains supplementary material, which is available to authorized users. Springer-Verlag 2012-02-21 2012 /pmc/articles/PMC7099890/ /pubmed/22350959 http://dx.doi.org/10.1007/s15010-012-0245-6 Text en © Springer-Verlag 2012 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Clinical and Epidemiological Study
Stupica, D.
Lusa, L.
Petrovec, M.
Žigon, N.
Jevšnik, M.
Bogovič, P.
Strle, F.
Respiratory viruses in patients and employees in an intensive care unit
title Respiratory viruses in patients and employees in an intensive care unit
title_full Respiratory viruses in patients and employees in an intensive care unit
title_fullStr Respiratory viruses in patients and employees in an intensive care unit
title_full_unstemmed Respiratory viruses in patients and employees in an intensive care unit
title_short Respiratory viruses in patients and employees in an intensive care unit
title_sort respiratory viruses in patients and employees in an intensive care unit
topic Clinical and Epidemiological Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099890/
https://www.ncbi.nlm.nih.gov/pubmed/22350959
http://dx.doi.org/10.1007/s15010-012-0245-6
work_keys_str_mv AT stupicad respiratoryvirusesinpatientsandemployeesinanintensivecareunit
AT lusal respiratoryvirusesinpatientsandemployeesinanintensivecareunit
AT petrovecm respiratoryvirusesinpatientsandemployeesinanintensivecareunit
AT zigonn respiratoryvirusesinpatientsandemployeesinanintensivecareunit
AT jevsnikm respiratoryvirusesinpatientsandemployeesinanintensivecareunit
AT bogovicp respiratoryvirusesinpatientsandemployeesinanintensivecareunit
AT strlef respiratoryvirusesinpatientsandemployeesinanintensivecareunit