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Effect of Protein Binding on Exposure of Unbound and Total Mycophenolic Acid: A Population Pharmacokinetic Analysis in Chinese Adult Kidney Transplant Recipients

OBJECTIVES: The population pharmacokinetic (popPK) characteristics of total mycophenolic acid (tMPA) have been investigated in various ethnic populations. However, investigations of popPK of unbound MPA (uMPA) are few. Thus, a popPK analysis was performed to: (1) characterize the PK of uMPA and tMPA...

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Detalles Bibliográficos
Autores principales:	Sheng, Changcheng, Zhao, Qun, Niu, Wanjie, Qiu, Xiaoyan, Zhang, Ming, Jiao, Zheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100081/ https://www.ncbi.nlm.nih.gov/pubmed/32265712 http://dx.doi.org/10.3389/fphar.2020.00340

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