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Crossing barriers: infections of the lung and the gut

Although known as respiratory pathogens, severe acute respiratory syndrome (SARS) and its sister coronaviruses frequently cause enteric symptoms. In addition, other classically non-enteric viruses (such as HIV and influenza) may also have enteric effects that are crucial in their pathogeneses. These...

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Autor principal: Openshaw, P J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100545/
https://www.ncbi.nlm.nih.gov/pubmed/19129753
http://dx.doi.org/10.1038/mi.2008.79
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author Openshaw, P J
author_facet Openshaw, P J
author_sort Openshaw, P J
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description Although known as respiratory pathogens, severe acute respiratory syndrome (SARS) and its sister coronaviruses frequently cause enteric symptoms. In addition, other classically non-enteric viruses (such as HIV and influenza) may also have enteric effects that are crucial in their pathogeneses. These effects can be due to direct infection of the gut mucosa, but can also be because of decreased antibacterial defenses, increased mucosal permeability, bacterial translocation, and systemic leak of endotoxin. SUPPLEMENTARY INFORMATION: The online version of this article (doi:10.1038/mi.2008.79) contains supplementary material, which is available to authorized users.
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spelling pubmed-71005452020-03-27 Crossing barriers: infections of the lung and the gut Openshaw, P J Mucosal Immunol Article Although known as respiratory pathogens, severe acute respiratory syndrome (SARS) and its sister coronaviruses frequently cause enteric symptoms. In addition, other classically non-enteric viruses (such as HIV and influenza) may also have enteric effects that are crucial in their pathogeneses. These effects can be due to direct infection of the gut mucosa, but can also be because of decreased antibacterial defenses, increased mucosal permeability, bacterial translocation, and systemic leak of endotoxin. SUPPLEMENTARY INFORMATION: The online version of this article (doi:10.1038/mi.2008.79) contains supplementary material, which is available to authorized users. Nature Publishing Group US 2008-12-24 2009 /pmc/articles/PMC7100545/ /pubmed/19129753 http://dx.doi.org/10.1038/mi.2008.79 Text en © Society for Mucosal Immunology Ltd 2009 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Openshaw, P J
Crossing barriers: infections of the lung and the gut
title Crossing barriers: infections of the lung and the gut
title_full Crossing barriers: infections of the lung and the gut
title_fullStr Crossing barriers: infections of the lung and the gut
title_full_unstemmed Crossing barriers: infections of the lung and the gut
title_short Crossing barriers: infections of the lung and the gut
title_sort crossing barriers: infections of the lung and the gut
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100545/
https://www.ncbi.nlm.nih.gov/pubmed/19129753
http://dx.doi.org/10.1038/mi.2008.79
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