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Crossing barriers: infections of the lung and the gut
Although known as respiratory pathogens, severe acute respiratory syndrome (SARS) and its sister coronaviruses frequently cause enteric symptoms. In addition, other classically non-enteric viruses (such as HIV and influenza) may also have enteric effects that are crucial in their pathogeneses. These...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group US
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100545/ https://www.ncbi.nlm.nih.gov/pubmed/19129753 http://dx.doi.org/10.1038/mi.2008.79 |
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author | Openshaw, P J |
author_facet | Openshaw, P J |
author_sort | Openshaw, P J |
collection | PubMed |
description | Although known as respiratory pathogens, severe acute respiratory syndrome (SARS) and its sister coronaviruses frequently cause enteric symptoms. In addition, other classically non-enteric viruses (such as HIV and influenza) may also have enteric effects that are crucial in their pathogeneses. These effects can be due to direct infection of the gut mucosa, but can also be because of decreased antibacterial defenses, increased mucosal permeability, bacterial translocation, and systemic leak of endotoxin. SUPPLEMENTARY INFORMATION: The online version of this article (doi:10.1038/mi.2008.79) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-7100545 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | Nature Publishing Group US |
record_format | MEDLINE/PubMed |
spelling | pubmed-71005452020-03-27 Crossing barriers: infections of the lung and the gut Openshaw, P J Mucosal Immunol Article Although known as respiratory pathogens, severe acute respiratory syndrome (SARS) and its sister coronaviruses frequently cause enteric symptoms. In addition, other classically non-enteric viruses (such as HIV and influenza) may also have enteric effects that are crucial in their pathogeneses. These effects can be due to direct infection of the gut mucosa, but can also be because of decreased antibacterial defenses, increased mucosal permeability, bacterial translocation, and systemic leak of endotoxin. SUPPLEMENTARY INFORMATION: The online version of this article (doi:10.1038/mi.2008.79) contains supplementary material, which is available to authorized users. Nature Publishing Group US 2008-12-24 2009 /pmc/articles/PMC7100545/ /pubmed/19129753 http://dx.doi.org/10.1038/mi.2008.79 Text en © Society for Mucosal Immunology Ltd 2009 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Article Openshaw, P J Crossing barriers: infections of the lung and the gut |
title | Crossing barriers: infections of the lung and the gut |
title_full | Crossing barriers: infections of the lung and the gut |
title_fullStr | Crossing barriers: infections of the lung and the gut |
title_full_unstemmed | Crossing barriers: infections of the lung and the gut |
title_short | Crossing barriers: infections of the lung and the gut |
title_sort | crossing barriers: infections of the lung and the gut |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100545/ https://www.ncbi.nlm.nih.gov/pubmed/19129753 http://dx.doi.org/10.1038/mi.2008.79 |
work_keys_str_mv | AT openshawpj crossingbarriersinfectionsofthelungandthegut |