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Alcohol consumption and employment: a cross-sectional study of office workers and unemployed people

BACKGROUND: Alcohol is a psychoactive substance with toxic and addictive properties. Biomarkers like GGT, AST, ALT and MCV are influenced by excessive ethanol consumption. Alcohol consumption represents a health risk and it has been linked to unemployment. The aim of this study how working status pr...

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Autores principales: De Sio, Simone, Tittarelli, Roberta, Di Martino, Giuseppe, Buomprisco, Giuseppe, Perri, Roberto, Bruno, Guglielmo, Pantano, Flaminia, Mannocchi, Giulio, Marinelli, Enrico, Cedrone, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100587/
https://www.ncbi.nlm.nih.gov/pubmed/32231881
http://dx.doi.org/10.7717/peerj.8774
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author De Sio, Simone
Tittarelli, Roberta
Di Martino, Giuseppe
Buomprisco, Giuseppe
Perri, Roberto
Bruno, Guglielmo
Pantano, Flaminia
Mannocchi, Giulio
Marinelli, Enrico
Cedrone, Fabrizio
author_facet De Sio, Simone
Tittarelli, Roberta
Di Martino, Giuseppe
Buomprisco, Giuseppe
Perri, Roberto
Bruno, Guglielmo
Pantano, Flaminia
Mannocchi, Giulio
Marinelli, Enrico
Cedrone, Fabrizio
author_sort De Sio, Simone
collection PubMed
description BACKGROUND: Alcohol is a psychoactive substance with toxic and addictive properties. Biomarkers like GGT, AST, ALT and MCV are influenced by excessive ethanol consumption. Alcohol consumption represents a health risk and it has been linked to unemployment. The aim of this study how working status predict alcohol consumption through a cross sectional study comparing alcohol-related biomarkers levels in office workers and unemployed people. METHODS: This study includes 157 office workers and 157 unemployed people, who were recruited from January to December 2018. A propensity score matching procedure was applied to obtain two homogenous groups in terms of age and gender. A non-parametric analysis was performed on serum biomarkers that are generally altered by alcohol consumption. Logistic regression models were designed to evaluate how working status predict abnormal biomarker levels related with alcohol consumption. RESULTS: No differences in median biomarker values were found between groups. Logistic regression analysis showed that office work is a negative predictor of pathological biomarker levels. Office workers had a significant relation with the levels of GGT (OR 0.48; 95% CI [0.28–0.84]), AST (OR 0.42; 95% CI [0.22–0.78]), ALT (OR 0.39; 95% CI [0.23–0.66]), and MCV (OR 0.37; 95% CI [0.19–0.70]). CONCLUSION: Office workers had lower absolute frequencies of pathological values of alcohol consumption biomarkers, after matching for age and gender compared with unemployed people. In addition, a significant negative association between office work is a negative predictor of biomarker levels of alcohol consumption. These results showed that work is an important determinant of health and that can represent a benefit for workers in terms of reducing the risk of consuming alcohol.
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spelling pubmed-71005872020-03-30 Alcohol consumption and employment: a cross-sectional study of office workers and unemployed people De Sio, Simone Tittarelli, Roberta Di Martino, Giuseppe Buomprisco, Giuseppe Perri, Roberto Bruno, Guglielmo Pantano, Flaminia Mannocchi, Giulio Marinelli, Enrico Cedrone, Fabrizio PeerJ Global Health BACKGROUND: Alcohol is a psychoactive substance with toxic and addictive properties. Biomarkers like GGT, AST, ALT and MCV are influenced by excessive ethanol consumption. Alcohol consumption represents a health risk and it has been linked to unemployment. The aim of this study how working status predict alcohol consumption through a cross sectional study comparing alcohol-related biomarkers levels in office workers and unemployed people. METHODS: This study includes 157 office workers and 157 unemployed people, who were recruited from January to December 2018. A propensity score matching procedure was applied to obtain two homogenous groups in terms of age and gender. A non-parametric analysis was performed on serum biomarkers that are generally altered by alcohol consumption. Logistic regression models were designed to evaluate how working status predict abnormal biomarker levels related with alcohol consumption. RESULTS: No differences in median biomarker values were found between groups. Logistic regression analysis showed that office work is a negative predictor of pathological biomarker levels. Office workers had a significant relation with the levels of GGT (OR 0.48; 95% CI [0.28–0.84]), AST (OR 0.42; 95% CI [0.22–0.78]), ALT (OR 0.39; 95% CI [0.23–0.66]), and MCV (OR 0.37; 95% CI [0.19–0.70]). CONCLUSION: Office workers had lower absolute frequencies of pathological values of alcohol consumption biomarkers, after matching for age and gender compared with unemployed people. In addition, a significant negative association between office work is a negative predictor of biomarker levels of alcohol consumption. These results showed that work is an important determinant of health and that can represent a benefit for workers in terms of reducing the risk of consuming alcohol. PeerJ Inc. 2020-03-24 /pmc/articles/PMC7100587/ /pubmed/32231881 http://dx.doi.org/10.7717/peerj.8774 Text en ©2020 De Sio et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.
spellingShingle Global Health
De Sio, Simone
Tittarelli, Roberta
Di Martino, Giuseppe
Buomprisco, Giuseppe
Perri, Roberto
Bruno, Guglielmo
Pantano, Flaminia
Mannocchi, Giulio
Marinelli, Enrico
Cedrone, Fabrizio
Alcohol consumption and employment: a cross-sectional study of office workers and unemployed people
title Alcohol consumption and employment: a cross-sectional study of office workers and unemployed people
title_full Alcohol consumption and employment: a cross-sectional study of office workers and unemployed people
title_fullStr Alcohol consumption and employment: a cross-sectional study of office workers and unemployed people
title_full_unstemmed Alcohol consumption and employment: a cross-sectional study of office workers and unemployed people
title_short Alcohol consumption and employment: a cross-sectional study of office workers and unemployed people
title_sort alcohol consumption and employment: a cross-sectional study of office workers and unemployed people
topic Global Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100587/
https://www.ncbi.nlm.nih.gov/pubmed/32231881
http://dx.doi.org/10.7717/peerj.8774
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