Cargando…

Non-invasive Detection of Exosomal MicroRNAs via Tethered Cationic Lipoplex Nanoparticles (tCLN) Biochip for Lung Cancer Early Detection

Circulating microRNAs carried by exosomes have emerged as promising diagnostic biomarkers for cancer because of their abundant amount and remarkable stability in body fluids. Exosomal microRNAs in blood are typically quantified using the RNA isolation-qRT-PCR workflow, which cannot distinguish circu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Chang, Kannisto, Eric, Yu, Guan, Yang, Yunchen, Reid, Mary E., Patnaik, Santosh K., Wu, Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100709/ https://www.ncbi.nlm.nih.gov/pubmed/32265989 http://dx.doi.org/10.3389/fgene.2020.00258

Ejemplares similares

Elevated expression of exosomal microRNA-21 as a potential biomarker for the early diagnosis of pancreatic cancer using a tethered cationic lipoplex nanoparticle biochip
por: Pu, Xiaofan, et al.
Publicado: (2020)

Extracellular mRNA detected by molecular beacons in tethered lipoplex nanoparticles for diagnosis of human hepatocellular carcinoma
por: Wang, Xinmei, et al.
Publicado: (2018)

Trichain cationic lipids: the potential of their lipoplexes for gene delivery
por: Kudsiova, Laila, et al.
Publicado: (2019)

Long-term safety and dose escalation of intracerebroventricular CLN5 gene therapy in sheep supports clinical translation for CLN5 Batten disease
por: Mitchell, Nadia L., et al.
Publicado: (2023)

Therapeutic Delivery of MicroRNA-29b by Cationic Lipoplexes for Lung Cancer
por: Wu, Yun, et al.
Publicado: (2013)

An altered transcriptome underlies cln5-deficiency phenotypes in Dictyostelium discoideum
por: Kim, William D., et al.
Publicado: (2022)

Factors affecting the yield of microRNAs from laser microdissectates of formalin-fixed tissue sections
por: Patnaik, Santosh Kumar, et al.
Publicado: (2012)

Probing the in vitro mechanism of action of cationic lipid/DNA lipoplexes at a nanometric scale
por: Le Bihan, Olivier, et al.
Publicado: (2011)

A signal-amplifiable biochip quantifies extracellular vesicle-associated RNAs for early cancer detection
por: Hu, Jiaming, et al.
Publicado: (2017)

Novel polymeric biochips for enhanced detection of infectious diseases
por: Hosseini, Samira, et al.
Publicado: (2016)

Biochip sensors for the rapid and sensitive detection of viral disease
por: Livingston, Andrew D, et al.
Publicado: (2005)

Controlled pDNA Release in Gemini Cationic Lipoplexes by Femtosecond Laser Irradiation of Gold Nanostars
por: Sánchez-Arribas, Natalia, et al.
Publicado: (2021)

PEGylation and folic-acid functionalization of cationic lipoplexes—Improved nucleic acid transfer into cancer cells
por: Hoffmann, Marco, et al.
Publicado: (2022)

Early postnatal administration of an AAV9 gene therapy is safe and efficacious in CLN3 disease
por: Johnson, Tyler B., et al.
Publicado: (2023)

Functional Analysis of a Novel CLN5 Mutation Identified in a Patient With Neuronal Ceroid Lipofuscinosis
por: Luo, Sukun, et al.
Publicado: (2020)

Exosomal miRNAs as Biomarkers for Prostate Cancer
por: Hessvik, Nina Pettersen, et al.
Publicado: (2013)

Tetherin is an exosomal tether
por: Edgar, James R, et al.
Publicado: (2016)

Efficient detection of RNA–protein interactions using tethered RNAs
por: Iioka, Hidekazu, et al.
Publicado: (2011)

Exploration of Long Non-coding RNAs and Circular RNAs in Porcine Milk Exosomes
por: Zeng, Bin, et al.
Publicado: (2020)

Overexpression of the Lung Cancer-Prognostic miR-146b MicroRNAs Has a Minimal and Negative Effect on the Malignant Phenotype of A549 Lung Cancer Cells
por: Patnaik, Santosh Kumar, et al.
Publicado: (2011)

Detection of Exosomal PD-L1 RNA in Saliva of Patients With Periodontitis
por: Yu, Jialiang, et al.
Publicado: (2019)

Exosomal miRNAs: Biological Properties and Therapeutic Potential
por: Hu, Guoku, et al.
Publicado: (2012)

Editorial: Exosomes, miRNAs, and lncRNAs in breast cancer: Therapeutic and diagnostic applications
por: Hashemi, Zahra Sadat, et al.
Publicado: (2023)

Intensified biochip system using chemiluminescence for the detection of Bacillus globigii spores
por: Stratis-Cullum, Dimitra N., et al.
Publicado: (2008)

Identification of pathogenic microbial cells and spores by electrochemical detection on a biochip
por: Gabig-Ciminska, Magdalena, et al.
Publicado: (2004)

Biochips for Direct Detection and Identification of Bacteria in Blood Culture-Like Conditions
por: Templier, V., et al.
Publicado: (2017)

Microfabricated passive resonator biochip for sensitive radiofrequency detection and characterization of glucose
por: Koirala, Gyan Raj, et al.
Publicado: (2018)

Real-time PCR biochip for on-site detection of Coxiella burnetii in ticks
por: Truong, A.-Tai, et al.
Publicado: (2021)

Electrochemical Gene Amplification Signal Detection of Disposable Biochips Using Electrodes
por: Kim, Gyo-Rim, et al.
Publicado: (2022)

microRNA Detection via Nanostructured Biochips for Early Cancer Diagnostics
por: Martino, Sara, et al.
Publicado: (2023)

Programmable Digital-Microfluidic Biochips for SARS-CoV-2 Detection
por: Wang, Yuxin, et al.
Publicado: (2023)

Optimal combination of cationic lipid and phospholipid in cationic liposomes for gene knockdown in breast cancer cells and mouse lung using siRNA lipoplexes
por: Hattori, Yoshiyuki, et al.
Publicado: (2022)

Changes in DNA bending and flexing due to tethered cations detected by fluorescence resonance energy transfer
por: Williams, Sarah L., et al.
Publicado: (2006)

Exosomal miRNAs as novel avenues for breast cancer treatment
por: Singh, Tejveer, et al.
Publicado: (2023)

Computational methods for ab initio detection of microRNAs
por: Allmer, Jens, et al.
Publicado: (2012)

Expression of MicroRNAs in the NCI-60 Cancer Cell-Lines
por: Patnaik, Santosh K., et al.
Publicado: (2012)

Osteoporosis Is Characterized by Altered Expression of Exosomal Long Non-coding RNAs
por: Teng, Zhaowei, et al.
Publicado: (2020)

Exosome-encapsulated ncRNAs: Emerging yin and yang of tumor hallmarks
por: Khan, Nazoora, et al.
Publicado: (2022)

A Novel CLN6 Variant Associated With Juvenile Neuronal Ceroid Lipofuscinosis in Patients With Absence of Visual Loss as a Presenting Feature
por: Nicolaou, Paschalis, et al.
Publicado: (2021)

Biomolecules Detection Using a Silver-Enhanced Gold Nanoparticle-Based Biochip
por: Liu, Yang, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_n4sqij02t9fpucv7q8finfodpm