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Chain Alignment of Collagen I Deciphered using Computationally Designed Heterotrimers

The most abundant member of the collagen protein family, collagen I (COL1), is composed of two similar (chain A) and one unique (chain B) polypeptides that self-assemble with one amino acid offset into a heterotrimeric triple helix. Given the offset, chain B can occupy either the leading (BAA), midd...

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Detalles Bibliográficos
Autores principales: Jalan, Abhishek A., Sammon, Douglas, Hartgerink, Jeffrey D., Brear, Paul, Stott, Katherine, Hamaia, Samir W., Hunter, Emma J., Walker, Douglas R., Leitinger, Birgit, Farndale, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100791/
https://www.ncbi.nlm.nih.gov/pubmed/31907373
http://dx.doi.org/10.1038/s41589-019-0435-y

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