Heart Failure With Preserved Ejection Fraction and Obesity: Syndrome of cGMP-PKG Deficiency in Post-Menopausal Women

This report describes a case of heart failure with preserved ejection fraction in a post-menopausal woman with obesity. The case highlights a metabolic phenotype of heart failure with preserved ejection fraction that commonly manifests in women, with the discussion focusing on pathophysiology, mecha...

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Detalles Bibliográficos
Autores principales: Sinha, Arjun, Yancy, Clyde W., Shah, Sanjiv J., Khan, Sadiya S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100876/
https://www.ncbi.nlm.nih.gov/pubmed/32226944
http://dx.doi.org/10.1016/j.jaccas.2019.11.065
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author Sinha, Arjun
Yancy, Clyde W.
Shah, Sanjiv J.
Khan, Sadiya S.
author_facet Sinha, Arjun
Yancy, Clyde W.
Shah, Sanjiv J.
Khan, Sadiya S.
author_sort Sinha, Arjun
collection PubMed
description This report describes a case of heart failure with preserved ejection fraction in a post-menopausal woman with obesity. The case highlights a metabolic phenotype of heart failure with preserved ejection fraction that commonly manifests in women, with the discussion focusing on pathophysiology, mechanistic pathways, and potential targeted therapeutic strategies. (Level of Difficulty: Intermediate.)
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spelling pubmed-71008762021-01-01 Heart Failure With Preserved Ejection Fraction and Obesity: Syndrome of cGMP-PKG Deficiency in Post-Menopausal Women Sinha, Arjun Yancy, Clyde W. Shah, Sanjiv J. Khan, Sadiya S. JACC Case Rep Case Report This report describes a case of heart failure with preserved ejection fraction in a post-menopausal woman with obesity. The case highlights a metabolic phenotype of heart failure with preserved ejection fraction that commonly manifests in women, with the discussion focusing on pathophysiology, mechanistic pathways, and potential targeted therapeutic strategies. (Level of Difficulty: Intermediate.) Elsevier 2020-01-15 /pmc/articles/PMC7100876/ /pubmed/32226944 http://dx.doi.org/10.1016/j.jaccas.2019.11.065 Text en © 2020 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Sinha, Arjun
Yancy, Clyde W.
Shah, Sanjiv J.
Khan, Sadiya S.
Heart Failure With Preserved Ejection Fraction and Obesity: Syndrome of cGMP-PKG Deficiency in Post-Menopausal Women
title Heart Failure With Preserved Ejection Fraction and Obesity: Syndrome of cGMP-PKG Deficiency in Post-Menopausal Women
title_full Heart Failure With Preserved Ejection Fraction and Obesity: Syndrome of cGMP-PKG Deficiency in Post-Menopausal Women
title_fullStr Heart Failure With Preserved Ejection Fraction and Obesity: Syndrome of cGMP-PKG Deficiency in Post-Menopausal Women
title_full_unstemmed Heart Failure With Preserved Ejection Fraction and Obesity: Syndrome of cGMP-PKG Deficiency in Post-Menopausal Women
title_short Heart Failure With Preserved Ejection Fraction and Obesity: Syndrome of cGMP-PKG Deficiency in Post-Menopausal Women
title_sort heart failure with preserved ejection fraction and obesity: syndrome of cgmp-pkg deficiency in post-menopausal women
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100876/
https://www.ncbi.nlm.nih.gov/pubmed/32226944
http://dx.doi.org/10.1016/j.jaccas.2019.11.065
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AT shahsanjivj heartfailurewithpreservedejectionfractionandobesitysyndromeofcgmppkgdeficiencyinpostmenopausalwomen
AT khansadiyas heartfailurewithpreservedejectionfractionandobesitysyndromeofcgmppkgdeficiencyinpostmenopausalwomen

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