Cargando…

A molecular network regulating the pro-inflammatory phenotype of human memory T lymphocytes

Understanding the mechanisms that modulate T helper lymphocyte functions is crucial to decipher normal and pathogenic immune responses in humans. To identify molecular determinants influencing the pathogenicity of T cells, we separated ex vivo-isolated primary human memory T lymphocytes based on the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Emming, Stefan, Bianchi, Niccolò, Polletti, Sara, Balestrieri, Chiara, Leoni, Cristina, Montagner, Sara, Chirichella, Michele, Delaleu, Nicolas, Natoli, Gioacchino, Monticelli, Silvia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100912/ https://www.ncbi.nlm.nih.gov/pubmed/32205878 http://dx.doi.org/10.1038/s41590-020-0622-8

Ejemplares similares

Vitamin D and IFN-β Modulate the Inflammatory Gene Expression Program of Primary Human T Lymphocytes
por: Bianchi, Niccolò, et al.
Publicado: (2020)

RFX transcription factors control a miR-150/PDAP1 axis that restrains the proliferation of human T cells
por: Chirichella, Michele, et al.
Publicado: (2022)

An optimized workflow for CRISPR-Cas9 deletion of surface and intracellular factors in primary human T lymphocytes
por: Leoni, Cristina, et al.
Publicado: (2021)

H3K9 trimethylation in active chromatin restricts the usage of functional CTCF sites in SINE B2 repeats
por: Gualdrini, Francesco, et al.
Publicado: (2022)

Dissection of acute stimulus-inducible nucleosome remodeling in mammalian cells
por: Comoglio, Federico, et al.
Publicado: (2019)

MicroRNAs in hematopoietic development
por: Montagner, Sara, et al.
Publicado: (2014)

Ex vivo microRNA and gene expression profiling of human Tr1‐like cells suggests a role for miR‐92a and ‐125a in the regulation of EOMES and IL‐10R
por: De Simone, Marco, et al.
Publicado: (2021)

Sustained activation of detoxification pathways promotes liver carcinogenesis in response to chronic bile acid-mediated damage
por: Collino, Agnese, et al.
Publicado: (2018)

A Large Fraction of Extragenic RNA Pol II Transcription Sites Overlap Enhancers
por: De Santa, Francesca, et al.
Publicado: (2010)

A first exon termination checkpoint preferentially suppresses extragenic transcription
por: Austenaa, Liv M.I., et al.
Publicado: (2021)

High constitutive activity of a broad panel of housekeeping and tissue-specific cis-regulatory elements depends on a subset of ETS proteins
por: Curina, Alessia, et al.
Publicado: (2017)

WDR5 inhibition halts metastasis dissemination by repressing the mesenchymal phenotype of breast cancer cells
por: Punzi, Simona, et al.
Publicado: (2019)

Proceedings of the 3rd ESRO Summer School in Space Physics on Electromagnetic Radiation in Space
por: Emming, J
Publicado: (1967)

Misinformation lingers in memory: Failure of three pro-vaccination strategies
por: Pluviano, Sara, et al.
Publicado: (2017)

Altered fractalkine cleavage results in an organ-specific 17 kDa fractalkine fragment in salivary glands of NOD mice
por: Delaleu, Nicolas, et al.
Publicado: (2008)

Click Pt(IV)-Carbohydrates Pro-Drugs for Treatment of Osteosarcoma
por: Moynihan, Eoin, et al.
Publicado: (2021)

Epigenetic and transcriptional control of mast cell responses
por: Monticelli, Silvia, et al.
Publicado: (2017)

A shortcut for early macrophage recruitment into tumors by activated oncogenes
por: Austenaa, Liv, et al.
Publicado: (2017)

The PPARγ2 Pro12Ala variant is protective against progression of nephropathy in people with type 2 diabetes
por: Lapice, Emanuela, et al.
Publicado: (2015)

Human Neutrophils Produce CCL23 in Response to Various TLR-Agonists and TNFα
por: Arruda-Silva, Fabio, et al.
Publicado: (2017)

Gambiense Human African Trypanosomiasis and Immunological Memory: Effect on Phenotypic Lymphocyte Profiles and Humoral Immunity
por: Lejon, Veerle, et al.
Publicado: (2014)

Functional Heterogeneity of CD4(+) Tumor-Infiltrating Lymphocytes With a Resident Memory Phenotype in NSCLC
por: Oja, Anna E., et al.
Publicado: (2018)

Memory-phenotype CD4(+) T Lymphocytes: A Novel Therapeutic Target in Infectious or Autoimmune Diseases?
por: Kawabe, Takeshi
Publicado: (2022)

Two Waves of Nuclear Factor κb Recruitment to Target Promoters
por: Saccani, Simona, et al.
Publicado: (2001)

Biomarker profiles in serum and saliva of experimental Sjögren's syndrome: associations with specific autoimmune manifestations
por: Delaleu, Nicolas, et al.
Publicado: (2008)

Magnusiomyces clavatus infection in a child after allogeneic hematotopoetic stem cell transplantation: Diagnostic and therapeutic implications
por: Leoni, Massimiliano, et al.
Publicado: (2018)

Reevaluation of ATR signaling in primary resting chronic lymphocytic leukemia cells: evidence for pro-survival or pro-apoptotic function
por: Beyaert, Maxime, et al.
Publicado: (2017)

Requirements for the differentiation of innate T-bet(high) memory-phenotype CD4(+) T lymphocytes under steady state
por: Kawabe, Takeshi, et al.
Publicado: (2020)

Comprehensive phenotyping of human peripheral blood B lymphocytes in healthy conditions
por: Carsetti, Rita, et al.
Publicado: (2021)

Role of Mixed Reflux and Hypomotility with Delayed Reflux Clearance in Patients with Non-cardiac Chest Pain
por: Ribolsi, Mentore, et al.
Publicado: (2016)

Fish the ChIPs: a pipeline for automated genomic annotation of ChIP-Seq data
por: Barozzi, Iros, et al.
Publicado: (2011)

Sjögren's syndrome: studying the disease in mice
por: Delaleu, Nicolas, et al.
Publicado: (2011)

Microglial Pro-Inflammatory and Anti-Inflammatory Phenotypes Are Modulated by Translocator Protein Activation
por: Da Pozzo, Eleonora, et al.
Publicado: (2019)

Acetylation-Specific Interference by Anti-Histone H3K9ac Intrabody Results in Precise Modulation of Gene Expression
por: Lisi, Simonetta, et al.
Publicado: (2022)

CD69(+) memory T lymphocytes of the bone marrow and spleen express the signature transcripts of tissue‐resident memory T lymphocytes
por: Siracusa, Francesco, et al.
Publicado: (2019)

Lymphocyte senescence in COPD is associated with loss of glucocorticoid receptor expression by pro-inflammatory/cytotoxic lymphocytes
por: Hodge, Greg, et al.
Publicado: (2015)

Lymphocyte senescence in COPD is associated with decreased histone deacetylase 2 expression by pro-inflammatory lymphocytes
por: Hodge, Greg, et al.
Publicado: (2015)

Loss of Tff1 Promotes Pro-Inflammatory Phenotype with Increase in the Levels of RORγt+ T Lymphocytes and Il-17 in Mouse Gastric Neoplasia
por: Soutto, Mohammed, et al.
Publicado: (2017)

Phenotypic characterization of human cytolytic T lymphocytes in mixed lymphocyte culture
Publicado: (1981)

Degradation of Promoter-bound p65/RelA Is Essential for the Prompt Termination of the Nuclear Factor κB Response
por: Saccani, Simona, et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_4bubsf4e031lbh0h8ruackr5iv