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New strategies for Leptospira vaccine development based on LPS removal

Pathogenic spirochetes from genus Leptospira are etiologic agents of leptospirosis. Cellular vaccines against Leptospira infection often elicit mainly response against the LPS antigen of the serovars present in the formulation. There is no suitable protein candidate capable of replacing whole-cell v...

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Detalles Bibliográficos
Autores principales: Lauretti-Ferreira, Fabiana, Silva, Paloma L. D., Alcântara, Naiara M., Silva, Bruna F., Grabher, Isabele, Souza, Gisele O., Nakajima, Erika, Akamatsu, Milena A., Vasconcellos, Silvio A., Abreu, Patricia A. E., Carvalho, Eneas, Martins, Elizabeth A. L., Ho, Paulo L., da Silva, Josefa B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100938/
https://www.ncbi.nlm.nih.gov/pubmed/32218590
http://dx.doi.org/10.1371/journal.pone.0230460