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Intensified Short Symptom Screening Program for Dengue Infection during Pregnancy, India

Mosquitoborne diseases (e.g., malaria, dengue, and chikungunya) are endemic to India and pose diagnostic challenges during pregnancy. We evaluated an intensified short symptom screening program in India to diagnose dengue during pregnancy. During October 2017–January 2018, we screened pregnant women...

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Autores principales: Naik, Shilpa, Robinson, Matthew L., Alexander, Mallika, Chandanwale, Ajay, Sambarey, Pradip, Kinikar, Aarti, Bharadwaj, Renu, Sapkal, Gajanan N., Chebrolu, Puja, Deshpande, Prasad, Kulkarni, Vandana, Nimkar, Smita, Mave, Vidya, Gupta, Amita, Mathad, Jyoti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101120/
https://www.ncbi.nlm.nih.gov/pubmed/32186485
http://dx.doi.org/10.3201/eid2604.191476
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author Naik, Shilpa
Robinson, Matthew L.
Alexander, Mallika
Chandanwale, Ajay
Sambarey, Pradip
Kinikar, Aarti
Bharadwaj, Renu
Sapkal, Gajanan N.
Chebrolu, Puja
Deshpande, Prasad
Kulkarni, Vandana
Nimkar, Smita
Mave, Vidya
Gupta, Amita
Mathad, Jyoti
author_facet Naik, Shilpa
Robinson, Matthew L.
Alexander, Mallika
Chandanwale, Ajay
Sambarey, Pradip
Kinikar, Aarti
Bharadwaj, Renu
Sapkal, Gajanan N.
Chebrolu, Puja
Deshpande, Prasad
Kulkarni, Vandana
Nimkar, Smita
Mave, Vidya
Gupta, Amita
Mathad, Jyoti
author_sort Naik, Shilpa
collection PubMed
description Mosquitoborne diseases (e.g., malaria, dengue, and chikungunya) are endemic to India and pose diagnostic challenges during pregnancy. We evaluated an intensified short symptom screening program in India to diagnose dengue during pregnancy. During October 2017–January 2018, we screened pregnant women during antenatal surveillance for symptoms of mosquitoborne diseases (fever only, fever with conjunctivitis, fever with rash, or all 3 symptoms) within the previous 15 days. Of 5,843 pregnant women screened, 52 were enrolled and tested for dengue, chikungunya, and Zika viruses by using a Trioplex real-time reverse transcription PCR. Of 49 who had complete results, 7 (14%) were dengue positive. Of these ocular pain was seen in 4 (57%) and conjunctivitis in 7 (100%). Intensified symptom screening using conjunctivitis, in addition to rash, in pregnant women with fever might improve dengue case detection and can be included in routine symptom screening during pregnancy.
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spelling pubmed-71011202020-04-03 Intensified Short Symptom Screening Program for Dengue Infection during Pregnancy, India Naik, Shilpa Robinson, Matthew L. Alexander, Mallika Chandanwale, Ajay Sambarey, Pradip Kinikar, Aarti Bharadwaj, Renu Sapkal, Gajanan N. Chebrolu, Puja Deshpande, Prasad Kulkarni, Vandana Nimkar, Smita Mave, Vidya Gupta, Amita Mathad, Jyoti Emerg Infect Dis Research Mosquitoborne diseases (e.g., malaria, dengue, and chikungunya) are endemic to India and pose diagnostic challenges during pregnancy. We evaluated an intensified short symptom screening program in India to diagnose dengue during pregnancy. During October 2017–January 2018, we screened pregnant women during antenatal surveillance for symptoms of mosquitoborne diseases (fever only, fever with conjunctivitis, fever with rash, or all 3 symptoms) within the previous 15 days. Of 5,843 pregnant women screened, 52 were enrolled and tested for dengue, chikungunya, and Zika viruses by using a Trioplex real-time reverse transcription PCR. Of 49 who had complete results, 7 (14%) were dengue positive. Of these ocular pain was seen in 4 (57%) and conjunctivitis in 7 (100%). Intensified symptom screening using conjunctivitis, in addition to rash, in pregnant women with fever might improve dengue case detection and can be included in routine symptom screening during pregnancy. Centers for Disease Control and Prevention 2020-04 /pmc/articles/PMC7101120/ /pubmed/32186485 http://dx.doi.org/10.3201/eid2604.191476 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Naik, Shilpa
Robinson, Matthew L.
Alexander, Mallika
Chandanwale, Ajay
Sambarey, Pradip
Kinikar, Aarti
Bharadwaj, Renu
Sapkal, Gajanan N.
Chebrolu, Puja
Deshpande, Prasad
Kulkarni, Vandana
Nimkar, Smita
Mave, Vidya
Gupta, Amita
Mathad, Jyoti
Intensified Short Symptom Screening Program for Dengue Infection during Pregnancy, India
title Intensified Short Symptom Screening Program for Dengue Infection during Pregnancy, India
title_full Intensified Short Symptom Screening Program for Dengue Infection during Pregnancy, India
title_fullStr Intensified Short Symptom Screening Program for Dengue Infection during Pregnancy, India
title_full_unstemmed Intensified Short Symptom Screening Program for Dengue Infection during Pregnancy, India
title_short Intensified Short Symptom Screening Program for Dengue Infection during Pregnancy, India
title_sort intensified short symptom screening program for dengue infection during pregnancy, india
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101120/
https://www.ncbi.nlm.nih.gov/pubmed/32186485
http://dx.doi.org/10.3201/eid2604.191476
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