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Heterozygous rare genetic variants in non-syndromic early-onset obesity
BACKGROUND: Obesity is a very heterogeneous disorder at both the clinical and molecular levels and with high heritability. Several monogenic forms and genes with strong effects have been identified for non-syndromic severe obesity. Novel therapeutic interventions are in development for some genetic...
Autores principales: | Serra-Juhé, Clara, Martos-Moreno, Gabriel Á., Bou de Pieri, Francesc, Flores, Raquel, Chowen, Julie A., Pérez-Jurado, Luis A., Argente, Jesús |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101277/ https://www.ncbi.nlm.nih.gov/pubmed/30926952 http://dx.doi.org/10.1038/s41366-019-0357-5 |
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