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Quantitative PET imaging of PD-L1 expression in xenograft and syngeneic tumour models using a site-specifically labelled PD-L1 antibody
PURPOSE: Despite remarkable clinical responses and prolonged survival across several cancers, not all patients benefit from PD-1/PD-L1 immune checkpoint blockade. Accordingly, assessment of tumour PD-L1 expression by immunohistochemistry (IHC) is increasingly applied to guide patient selection, ther...
Autores principales: | Christensen, Camilla, Kristensen, Lotte K., Alfsen, Maria Z., Nielsen, Carsten H., Kjaer, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101303/ https://www.ncbi.nlm.nih.gov/pubmed/31883023 http://dx.doi.org/10.1007/s00259-019-04646-4 |
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