Cargando…

Treatment with Anaerobutyricum soehngenii: a pilot study of safety and dose–response effects on glucose metabolism in human subjects with metabolic syndrome

Dysbiosis of the intestinal microbiota has been implicated in insulin resistance, although evidence regarding causality in humans is scarce. We performed a phase I/II dose-finding and safety study on the effect of oral intake of the anaerobic butyrogenic strain Anaerobutyricum soehngenii on glucose...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gilijamse, Pim W., Hartstra, Annick V., Levin, Evgeni, Wortelboer, Koen, Serlie, Mireille J., Ackermans, Mariette T., Herrema, Hilde, Nederveen, Aart J., Imangaliyev, Sultan, Aalvink, Steven, Sommer, Morton, Levels, Han, Stroes, Erik S. G., Groen, Albert K., Kemper, Marleen, de Vos, Willem M., Nieuwdorp, Max, Prodan, Andrei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101376/ https://www.ncbi.nlm.nih.gov/pubmed/32221294 http://dx.doi.org/10.1038/s41522-020-0127-0

Ejemplares similares

From fecal microbiota transplantation toward next-generation beneficial microbes: The case of Anaerobutyricum soehngenii
por: Wortelboer, Koen, et al.
Publicado: (2022)

Duodenal Anaerobutyricum soehngenii infusion stimulates GLP-1 production, ameliorates glycaemic control and beneficially shapes the duodenal transcriptome in metabolic syndrome subjects: a randomised double-blind placebo-controlled cross-over study
por: Koopen, Annefleur, et al.
Publicado: (2022)

Toxicological safety evaluation of live Anaerobutyricum soehngenii strain CH106
por: Seegers, Jos F. M. L., et al.
Publicado: (2021)

Infusion of donor feces affects the gut–brain axis in humans with metabolic syndrome
por: Hartstra, Annick V., et al.
Publicado: (2020)

Sexual Dimorphism in Hepatic, Adipose Tissue, and Peripheral Tissue Insulin Sensitivity in Obese Humans
por: ter Horst, Kasper W., et al.
Publicado: (2015)

Donor metabolic characteristics drive effects of faecal microbiota transplantation on recipient insulin sensitivity, energy expenditure and intestinal transit time
por: de Groot, Pieter, et al.
Publicado: (2020)

Correlation of plasma metabolites with glucose and lipid fluxes in human insulin resistance
por: Hartstra, Annick V., et al.
Publicado: (2020)

The Effect of a Diiodothyronine Mimetic on Insulin Sensitivity in Male Cardiometabolic Patients: A Double-Blind Randomized Controlled Trial
por: van der Valk, Fleur, et al.
Publicado: (2014)

Differential metabolic effects of oral butyrate treatment in lean versus metabolic syndrome subjects
por: Bouter, KEC, et al.
Publicado: (2018)

The FGF21 response to fructose predicts metabolic health and persists after bariatric surgery in obese humans
por: ter Horst, Kasper W., et al.
Publicado: (2017)

Hepatic Diacylglycerol-Associated Protein Kinase Cε Translocation Links Hepatic Steatosis to Hepatic Insulin Resistance in Humans
por: ter Horst, Kasper W., et al.
Publicado: (2017)

Metabolite Profile of Treatment-Naive Metabolic Syndrome Subjects in Relation to Cardiovascular Disease Risk
por: Warmbrunn, Moritz V., et al.
Publicado: (2021)

Fecal microbiota transplantation beyond Clostridioides difficile infections
por: Wortelboer, Koen, et al.
Publicado: (2019)

Phage-microbe dynamics after sterile faecal filtrate transplantation in individuals with metabolic syndrome: a double-blind, randomised, placebo-controlled clinical trial assessing efficacy and safety
por: Wortelboer, Koen, et al.
Publicado: (2023)

Hypercaloric diets with increased meal frequency, but not meal size, increase intrahepatic triglycerides: A randomized controlled trial
por: Koopman, Karin E, et al.
Publicado: (2014)

A Major Role for Perifornical Orexin Neurons in the Control of Glucose Metabolism in Rats
por: Yi, Chun-Xia, et al.
Publicado: (2009)

Anaerobutyricum and Subdoligranulum Are Differentially Enriched in Broilers with Disparate Weight Gains
por: Liu, Jing, et al.
Publicado: (2023)

Duodenal L cell density correlates with features of metabolic syndrome and plasma metabolites
por: van Baar, Annieke C G, et al.
Publicado: (2018)

Does disease start in the mouth, the gut or both?
por: Prodan, Andrei, et al.
Publicado: (2019)

Shedding light on dark matter – faecal microbiota transplantation in Europe
por: Wortelboer, Koen, et al.
Publicado: (2021)

Effect of Vegan Fecal Microbiota Transplantation on Carnitine‐ and Choline‐Derived Trimethylamine‐N‐Oxide Production and Vascular Inflammation in Patients With Metabolic Syndrome
por: Smits, Loek P., et al.
Publicado: (2018)

Effect of Fecal Microbiota Transplantation Combined With Mediterranean Diet on Insulin Sensitivity in Subjects With Metabolic Syndrome
por: Koopen, Annefleur M., et al.
Publicado: (2021)

Gut virome profiling identifies a widespread bacteriophage family associated with metabolic syndrome
por: de Jonge, Patrick A., et al.
Publicado: (2022)

Subthalamic nucleus stimulation does not influence basal glucose metabolism or insulin sensitivity in patients with Parkinson's disease
por: Lammers, Nicolette M., et al.
Publicado: (2014)

Unravelling lactate‐acetate and sugar conversion into butyrate by intestinal Anaerobutyricum and Anaerostipes species by comparative proteogenomics
por: Shetty, Sudarshan A., et al.
Publicado: (2020)

Species- and strain-level assessment using rrn long-amplicons suggests donor’s influence on gut microbial transference via fecal transplants in metabolic syndrome subjects
por: Benítez-Páez, Alfonso, et al.
Publicado: (2022)

Hepatic steatosis does not cause insulin resistance in people with familial hypobetalipoproteinaemia
por: Visser, M. E., et al.
Publicado: (2011)

Dynamic magnetic resonance measurements of calf muscle oxygenation and energy metabolism in peripheral artery disease
por: Bakermans, Adrianus J., et al.
Publicado: (2019)

Increased expression of key SARS-CoV-2 entry points in multiple tissues in individuals with NAFLD
por: Meijnikman, Abraham S., et al.
Publicado: (2021)

Bariatric surgery improves postprandial VLDL kinetics and restores insulin-mediated regulation of hepatic VLDL production
por: Yildirim, Vehpi, et al.
Publicado: (2023)

An evaluation of the therapeutic potential of fecal microbiota transplantation to treat infectious and metabolic diseases
por: Groen, Albert K, et al.
Publicado: (2016)

Serotonin Transporter Binding in the Diencephalon Is Reduced in Insulin-Resistant Obese Humans
por: Versteeg, Ruth I., et al.
Publicado: (2017)

The effect of dapagliflozin on apolipoprotein B and glucose fluxes in patients with type 2 diabetes and well‐controlled plasma LDL cholesterol
por: Bouter, Kristien E. C., et al.
Publicado: (2020)

Gut bacteriophage dynamics during fecal microbial transplantation in subjects with metabolic syndrome
por: Manrique, Pilar, et al.
Publicado: (2021)

Comparing bioinformatic pipelines for microbial 16S rRNA amplicon sequencing
por: Prodan, Andrei, et al.
Publicado: (2020)

Pituitary Adenylate Cyclase-Activating Polypeptide Stimulates Glucose Production via the Hepatic Sympathetic Innervation in Rats
por: Yi, Chun-Xia, et al.
Publicado: (2010)

Donor Fecal Microbiota Transplantation Alters Gut Microbiota and Metabolites in Obese Individuals With Steatohepatitis
por: Witjes, Julia J., et al.
Publicado: (2020)

Gut Microbiota as a Trigger for Metabolic Inflammation in Obesity and Type 2 Diabetes
por: Scheithauer, Torsten P. M., et al.
Publicado: (2020)

“Candidatus Galacturonibacter soehngenii” Shows Acetogenic Catabolism of Galacturonic Acid but Lacks a Canonical Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase Complex
por: Valk, Laura C., et al.
Publicado: (2020)

A Study of the Variation in the Salivary Peptide Profiles of Young Healthy Adults Acquired Using MALDI-TOF MS
por: Prodan, Andrei, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_0mt9q0augolkn75tclhd6stqon