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NLRP3 Inflammasome Activation Is Essential for Paraquat-Induced Acute Lung Injury

The innate immune response is important in paraquat-induced acute lung injury, but the exact pathways involved are not elucidated. The objectives of this study were to determine the specific role of the NLRP3 inflammasome in the process. Acute lung injury was induced by administering paraquat (PQ) i...

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Detalles Bibliográficos
Autores principales: Liu, Zhenning, Zhao, Hongyu, Liu, Wei, Li, Tiegang, Wang, Yu, Zhao, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101550/
https://www.ncbi.nlm.nih.gov/pubmed/25338942
http://dx.doi.org/10.1007/s10753-014-0048-2