Feasibility of conditioning with thymoglobulin and reduced intensity TBI to reduce acute GVHD in recipients of allogeneic SCT

Murine studies using anti-T-cell antibodies for conditioning in allogeneic SCT demonstrate engraftment with low rates of GVHD. On the basis of this preclinical model, we conditioned 30 patients with advanced hematologic malignancies with rabbit antithymocyte globulin (ATG) and TBI, to reduce rates o...

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Detalles Bibliográficos
Autores principales: Toor, A, Rodriguez, T, Bauml, M, Mathews, H, Shanti, S, Senitzer, D, Kini, A, Norton, J, Parthasarathy, M, Mohideen, N, Petrowsky, C, Bonilla, B, Smith, S, Stiff, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101790/
https://www.ncbi.nlm.nih.gov/pubmed/18711352
http://dx.doi.org/10.1038/bmt.2008.244

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