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Combined blockade of angiotensin II and prorenin receptors ameliorates podocytic apoptosis induced by IgA-activated mesangial cells

Glomerulo-podocytic communication plays an important role in the podocytic injury in IgA nephropathy (IgAN). In this study, we examine the role of podocytic angiotensin II receptor subtype 1 (AT1R) and prorenin receptor (PRR) in podocytic apoptosis in IgAN. Polymeric IgA (pIgA) was isolated from pat...

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Detalles Bibliográficos
Autores principales:	Leung, Joseph C. K., Chan, Loretta Y. Y., Saleem, M. A., Mathieson, P. W., Tang, Sydney C. W., Lai, Kar Neng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2015
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101871/ https://www.ncbi.nlm.nih.gov/pubmed/25808596 http://dx.doi.org/10.1007/s10495-015-1117-1

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