SOCS-1 Suppresses Inflammation Through Inhibition of NALP3 Inflammasome Formation in Smoke Inhalation-Induced Acute Lung Injury

Smoke inhalation leads to acute lung injury (ALI), a devastating clinical problem associated with high mortality rates. Suppressor of cytokine signaling-1 (SOCS-1) is a negative regulator of proinflammatory cytokine signaling. We have found that adenoviral gene transfer of SOCS-1 ameliorates smoke i...

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Detalles Bibliográficos
Autores principales: Zhang, Leifang, Xu, Chenming, Chen, Xiaoming, Shi, Qiwen, Su, Weike, Zhao, Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102050/
https://www.ncbi.nlm.nih.gov/pubmed/29907905
http://dx.doi.org/10.1007/s10753-018-0802-y

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