Fatal Outcome of a Hyperinfection Syndrome despite Successful Eradication of Strongyloides with Subcutaneous Ivermectin

We report the case of a 77–year–old man who developed a Strongyloides hyperinfection syndrome following immunosuppressive therapy more than 60 years after he moved away from an area endemic for Strongyloides stercoralis. Successful eradication of the nematode was achieved with an off label subcutane...

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Detalles Bibliográficos
Autores principales: Hauber, H. P., Galle, J., Chiodini, P. L., Rupp, J., Birke, R., Vollmer, E., Zabel, P., Lange, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Urban & Vogel 2005
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102170/
https://www.ncbi.nlm.nih.gov/pubmed/16258873
http://dx.doi.org/10.1007/s15010-005-5060-x
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author Hauber, H. P.
Galle, J.
Chiodini, P. L.
Rupp, J.
Birke, R.
Vollmer, E.
Zabel, P.
Lange, C.
author_facet Hauber, H. P.
Galle, J.
Chiodini, P. L.
Rupp, J.
Birke, R.
Vollmer, E.
Zabel, P.
Lange, C.
author_sort Hauber, H. P.
collection PubMed
description We report the case of a 77–year–old man who developed a Strongyloides hyperinfection syndrome following immunosuppressive therapy more than 60 years after he moved away from an area endemic for Strongyloides stercoralis. Successful eradication of the nematode was achieved with an off label subcutaneous formulation of ivermectin. However, the patient subsequently died from acute respiratory distress syndrome (ARDS). Despite a high wormload in the stool and sputum of the patient and delayed infection control measures in the hospital, testing of the medical staff revealed a very low risk of Strongyloides transmission among healthcare workers.
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spelling pubmed-71021702020-03-31 Fatal Outcome of a Hyperinfection Syndrome despite Successful Eradication of Strongyloides with Subcutaneous Ivermectin Hauber, H. P. Galle, J. Chiodini, P. L. Rupp, J. Birke, R. Vollmer, E. Zabel, P. Lange, C. Infection Case Report We report the case of a 77–year–old man who developed a Strongyloides hyperinfection syndrome following immunosuppressive therapy more than 60 years after he moved away from an area endemic for Strongyloides stercoralis. Successful eradication of the nematode was achieved with an off label subcutaneous formulation of ivermectin. However, the patient subsequently died from acute respiratory distress syndrome (ARDS). Despite a high wormload in the stool and sputum of the patient and delayed infection control measures in the hospital, testing of the medical staff revealed a very low risk of Strongyloides transmission among healthcare workers. Urban & Vogel 2005 /pmc/articles/PMC7102170/ /pubmed/16258873 http://dx.doi.org/10.1007/s15010-005-5060-x Text en © Urban & Vogel München 2005 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Case Report
Hauber, H. P.
Galle, J.
Chiodini, P. L.
Rupp, J.
Birke, R.
Vollmer, E.
Zabel, P.
Lange, C.
Fatal Outcome of a Hyperinfection Syndrome despite Successful Eradication of Strongyloides with Subcutaneous Ivermectin
title Fatal Outcome of a Hyperinfection Syndrome despite Successful Eradication of Strongyloides with Subcutaneous Ivermectin
title_full Fatal Outcome of a Hyperinfection Syndrome despite Successful Eradication of Strongyloides with Subcutaneous Ivermectin
title_fullStr Fatal Outcome of a Hyperinfection Syndrome despite Successful Eradication of Strongyloides with Subcutaneous Ivermectin
title_full_unstemmed Fatal Outcome of a Hyperinfection Syndrome despite Successful Eradication of Strongyloides with Subcutaneous Ivermectin
title_short Fatal Outcome of a Hyperinfection Syndrome despite Successful Eradication of Strongyloides with Subcutaneous Ivermectin
title_sort fatal outcome of a hyperinfection syndrome despite successful eradication of strongyloides with subcutaneous ivermectin
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102170/
https://www.ncbi.nlm.nih.gov/pubmed/16258873
http://dx.doi.org/10.1007/s15010-005-5060-x
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