Generation of outbred Ace2 knockout mice by RNA transfection of TALENs displaying colitis reminiscent pathophysiology and inflammation

The angiotensin I converting enzyme 2 (ACE2) is a key factor in the maintenance of intestinal homeostasis. Dysregulation of homeostasis can lead to inflammation of the colon (colitis), which can cause life-threatening enfeeblement or even cancer. Animal models are valuable surrogates in deciphering...

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Detalles Bibliográficos
Autores principales: Liu, Chuxin, Xiao, Liping, Li, Feida, Zhang, Huanhuan, Li, Qin, Liu, Huan, Fu, Shujin, Li, Chao, Zhang, Xingju, Wang, Jun, Staunstrup, Nicklas H., Li, Yong, Yang, Huanming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102211/
https://www.ncbi.nlm.nih.gov/pubmed/25448263
http://dx.doi.org/10.1007/s11248-014-9855-3

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