Severe Proctitis, Perforation, and Fatal Rectal Bleeding Secondary to Cytomegalovirus in an Immunocompetent Patient: Report of a Case

Cytomegalovirus (CMV) infection is associated with significant morbidity and mortality in immunocompromised patients. In immunocompetent individuals, the infection is usually subclinical but it can sometimes be life threatening. We describe a case of fatal CMV proctitis in a 71-year-old man followin...

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Autores principales: Alam, Imran, Shanoon, Divina, Alhamdani, Ali, Boyd, A., Griffiths, A.P., Baxter, J.N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102328/
https://www.ncbi.nlm.nih.gov/pubmed/17186350
http://dx.doi.org/10.1007/s00595-006-3335-1
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author Alam, Imran
Shanoon, Divina
Alhamdani, Ali
Boyd, A.
Griffiths, A.P.
Baxter, J.N.
author_facet Alam, Imran
Shanoon, Divina
Alhamdani, Ali
Boyd, A.
Griffiths, A.P.
Baxter, J.N.
author_sort Alam, Imran
collection PubMed
description Cytomegalovirus (CMV) infection is associated with significant morbidity and mortality in immunocompromised patients. In immunocompetent individuals, the infection is usually subclinical but it can sometimes be life threatening. We describe a case of fatal CMV proctitis in a 71-year-old man following an Ivor–Lewis esophagectomy. After surgery he developed renal failure, methicillin-resistant Staphylococcus aureus pneumonia, and acute respiratory distress syndrome. He recovered but developed melena and massive fresh rectal bleeding. Sigmoidoscopy revealed severe proctitis and a biopsy was consistent with ischemia. Despite undergoing a proctectomy he continued to bleed and died despite every effort. The final histological examination of the rectum revealed a CMV infection.
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spelling pubmed-71023282020-03-31 Severe Proctitis, Perforation, and Fatal Rectal Bleeding Secondary to Cytomegalovirus in an Immunocompetent Patient: Report of a Case Alam, Imran Shanoon, Divina Alhamdani, Ali Boyd, A. Griffiths, A.P. Baxter, J.N. Surg Today Article Cytomegalovirus (CMV) infection is associated with significant morbidity and mortality in immunocompromised patients. In immunocompetent individuals, the infection is usually subclinical but it can sometimes be life threatening. We describe a case of fatal CMV proctitis in a 71-year-old man following an Ivor–Lewis esophagectomy. After surgery he developed renal failure, methicillin-resistant Staphylococcus aureus pneumonia, and acute respiratory distress syndrome. He recovered but developed melena and massive fresh rectal bleeding. Sigmoidoscopy revealed severe proctitis and a biopsy was consistent with ischemia. Despite undergoing a proctectomy he continued to bleed and died despite every effort. The final histological examination of the rectum revealed a CMV infection. Springer-Verlag 2007-01-01 2007 /pmc/articles/PMC7102328/ /pubmed/17186350 http://dx.doi.org/10.1007/s00595-006-3335-1 Text en © Springer-Verlag Tokyo 2007 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Alam, Imran
Shanoon, Divina
Alhamdani, Ali
Boyd, A.
Griffiths, A.P.
Baxter, J.N.
Severe Proctitis, Perforation, and Fatal Rectal Bleeding Secondary to Cytomegalovirus in an Immunocompetent Patient: Report of a Case
title Severe Proctitis, Perforation, and Fatal Rectal Bleeding Secondary to Cytomegalovirus in an Immunocompetent Patient: Report of a Case
title_full Severe Proctitis, Perforation, and Fatal Rectal Bleeding Secondary to Cytomegalovirus in an Immunocompetent Patient: Report of a Case
title_fullStr Severe Proctitis, Perforation, and Fatal Rectal Bleeding Secondary to Cytomegalovirus in an Immunocompetent Patient: Report of a Case
title_full_unstemmed Severe Proctitis, Perforation, and Fatal Rectal Bleeding Secondary to Cytomegalovirus in an Immunocompetent Patient: Report of a Case
title_short Severe Proctitis, Perforation, and Fatal Rectal Bleeding Secondary to Cytomegalovirus in an Immunocompetent Patient: Report of a Case
title_sort severe proctitis, perforation, and fatal rectal bleeding secondary to cytomegalovirus in an immunocompetent patient: report of a case
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102328/
https://www.ncbi.nlm.nih.gov/pubmed/17186350
http://dx.doi.org/10.1007/s00595-006-3335-1
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