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The Effects of Inhibition of MicroRNA-375 in a Mouse Model of Doxorubicin-Induced Cardiac Toxicity

BACKGROUND: Doxorubicin-induced myocardial toxicity is associated with oxidative stress, cardiomyocyte, apoptosis, and loss of contractile function. Previous studies showed that microRNA-375 (miR-375) expression was increased in mouse models of heart failure and clinically, and that inhibition of mi...

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Detalles Bibliográficos
Autores principales: Zhang, Hao, Tian, Yikui, Liang, Degang, Fu, Qiang, Jia, Liqun, Wu, Dawei, Zhu, Xinyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102408/
https://www.ncbi.nlm.nih.gov/pubmed/32186283
http://dx.doi.org/10.12659/MSM.920557

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