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Mutant Huntingtin affects toll-like receptor 4 intracellular trafficking and cytokine production in mast cells

BACKGROUND: Huntington’s disease (HD) is caused by the expression of a mutated variant of Huntingtin (mHtt), which results in the complex pathology characterized by a defective function of the nervous system and altered inflammatory responses. While the neuronal effects of mHtt expression have been...

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Detalles Bibliográficos
Autores principales:	Pérez-Rodríguez, Marian Jesabel, Ibarra-Sánchez, Alfredo, Román-Figueroa, Abraham, Pérez-Severiano, Francisca, González-Espinosa, Claudia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102443/ https://www.ncbi.nlm.nih.gov/pubmed/32220257 http://dx.doi.org/10.1186/s12974-020-01758-9

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