Severe juvenile dermatomyositis: two patients complicated with extra musculocutaneous involvement

Here we report two patients with severe juvenile dermatomyositis (JDM) complicated with extra musculocutaneous involvement. The first case (a 10-year-old boy) had unusual initial presentation of JDM complicated with interstitial lung disease documented with high-resolution computed tomography. He ha...

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Detalles Bibliográficos
Autores principales: Tosun, Ayşe, Serdaroğlu, Gül, Aslan, Mehmet Tayyip, Polat, Muzaffer, Akalın, Taner, Tekgul, Hasan, Gökben, Sarenur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2006
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102511/
https://www.ncbi.nlm.nih.gov/pubmed/16721599
http://dx.doi.org/10.1007/s00296-006-0141-4
Descripción
Sumario:Here we report two patients with severe juvenile dermatomyositis (JDM) complicated with extra musculocutaneous involvement. The first case (a 10-year-old boy) had unusual initial presentation of JDM complicated with interstitial lung disease documented with high-resolution computed tomography. He had a rapidly progressive course and died in 7 weeks after the onset of the disease despite steroid and immunosuppressive treatment. The second case (a 14-year-old boy) was presented with myositis complicated with hepatitis. He also had a chronic course of JDM with unfavorable outcome. It appears that the prognosis of patients with severe JDM is related with the degree of autoimmune vasculitis on extra musculocutaneous involvement.

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