Severe juvenile dermatomyositis: two patients complicated with extra musculocutaneous involvement

Here we report two patients with severe juvenile dermatomyositis (JDM) complicated with extra musculocutaneous involvement. The first case (a 10-year-old boy) had unusual initial presentation of JDM complicated with interstitial lung disease documented with high-resolution computed tomography. He ha...

Descripción completa

Detalles Bibliográficos
Autores principales: Tosun, Ayşe, Serdaroğlu, Gül, Aslan, Mehmet Tayyip, Polat, Muzaffer, Akalın, Taner, Tekgul, Hasan, Gökben, Sarenur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2006
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102511/
https://www.ncbi.nlm.nih.gov/pubmed/16721599
http://dx.doi.org/10.1007/s00296-006-0141-4
_version_ 1783511840847822848
author Tosun, Ayşe
Serdaroğlu, Gül
Aslan, Mehmet Tayyip
Polat, Muzaffer
Akalın, Taner
Tekgul, Hasan
Gökben, Sarenur
author_facet Tosun, Ayşe
Serdaroğlu, Gül
Aslan, Mehmet Tayyip
Polat, Muzaffer
Akalın, Taner
Tekgul, Hasan
Gökben, Sarenur
author_sort Tosun, Ayşe
collection PubMed
description Here we report two patients with severe juvenile dermatomyositis (JDM) complicated with extra musculocutaneous involvement. The first case (a 10-year-old boy) had unusual initial presentation of JDM complicated with interstitial lung disease documented with high-resolution computed tomography. He had a rapidly progressive course and died in 7 weeks after the onset of the disease despite steroid and immunosuppressive treatment. The second case (a 14-year-old boy) was presented with myositis complicated with hepatitis. He also had a chronic course of JDM with unfavorable outcome. It appears that the prognosis of patients with severe JDM is related with the degree of autoimmune vasculitis on extra musculocutaneous involvement.
format Online
Article
Text
id pubmed-7102511
institution National Center for Biotechnology Information
language English
publishDate 2006
publisher Springer-Verlag
record_format MEDLINE/PubMed
spelling pubmed-71025112020-03-31 Severe juvenile dermatomyositis: two patients complicated with extra musculocutaneous involvement Tosun, Ayşe Serdaroğlu, Gül Aslan, Mehmet Tayyip Polat, Muzaffer Akalın, Taner Tekgul, Hasan Gökben, Sarenur Rheumatol Int Case Report Here we report two patients with severe juvenile dermatomyositis (JDM) complicated with extra musculocutaneous involvement. The first case (a 10-year-old boy) had unusual initial presentation of JDM complicated with interstitial lung disease documented with high-resolution computed tomography. He had a rapidly progressive course and died in 7 weeks after the onset of the disease despite steroid and immunosuppressive treatment. The second case (a 14-year-old boy) was presented with myositis complicated with hepatitis. He also had a chronic course of JDM with unfavorable outcome. It appears that the prognosis of patients with severe JDM is related with the degree of autoimmune vasculitis on extra musculocutaneous involvement. Springer-Verlag 2006-05-24 2006 /pmc/articles/PMC7102511/ /pubmed/16721599 http://dx.doi.org/10.1007/s00296-006-0141-4 Text en © Springer-Verlag 2006 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Case Report
Tosun, Ayşe
Serdaroğlu, Gül
Aslan, Mehmet Tayyip
Polat, Muzaffer
Akalın, Taner
Tekgul, Hasan
Gökben, Sarenur
Severe juvenile dermatomyositis: two patients complicated with extra musculocutaneous involvement
title Severe juvenile dermatomyositis: two patients complicated with extra musculocutaneous involvement
title_full Severe juvenile dermatomyositis: two patients complicated with extra musculocutaneous involvement
title_fullStr Severe juvenile dermatomyositis: two patients complicated with extra musculocutaneous involvement
title_full_unstemmed Severe juvenile dermatomyositis: two patients complicated with extra musculocutaneous involvement
title_short Severe juvenile dermatomyositis: two patients complicated with extra musculocutaneous involvement
title_sort severe juvenile dermatomyositis: two patients complicated with extra musculocutaneous involvement
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102511/
https://www.ncbi.nlm.nih.gov/pubmed/16721599
http://dx.doi.org/10.1007/s00296-006-0141-4
work_keys_str_mv AT tosunayse severejuveniledermatomyositistwopatientscomplicatedwithextramusculocutaneousinvolvement
AT serdaroglugul severejuveniledermatomyositistwopatientscomplicatedwithextramusculocutaneousinvolvement
AT aslanmehmettayyip severejuveniledermatomyositistwopatientscomplicatedwithextramusculocutaneousinvolvement
AT polatmuzaffer severejuveniledermatomyositistwopatientscomplicatedwithextramusculocutaneousinvolvement
AT akalıntaner severejuveniledermatomyositistwopatientscomplicatedwithextramusculocutaneousinvolvement
AT tekgulhasan severejuveniledermatomyositistwopatientscomplicatedwithextramusculocutaneousinvolvement
AT gokbensarenur severejuveniledermatomyositistwopatientscomplicatedwithextramusculocutaneousinvolvement

Ejemplares similares