Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

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The emergence of SARS-CoV-2 has resulted in >90,000 infections and >3,000 deaths. Coronavirus spike (S) glycoproteins promote entry into cells and are the main target of antibodies. We show that SARS-CoV-2 S uses ACE2 to enter cells and that the receptor-binding domains of SARS-CoV-2 S and SAR...

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Detalles Bibliográficos
Autores principales: Walls, Alexandra C., Park, Young-Jun, Tortorici, M. Alejandra, Wall, Abigail, McGuire, Andrew T., Veesler, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102599/
https://www.ncbi.nlm.nih.gov/pubmed/32155444
http://dx.doi.org/10.1016/j.cell.2020.02.058

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