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Pathogenicity and transmissibility of 2019-nCoV—A quick overview and comparison with other emerging viruses
A zoonotic coronavirus, tentatively labeled as 2019-nCoV by the World Health Organization (WHO), has been identified as the causative agent of the viral pneumonia outbreak in Wuhan, China, at the end of 2019. Although 2019-nCoV can cause a severe respiratory illness like SARS and MERS, evidence from...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Author(s). Published by Elsevier Masson SAS on behalf of Institut Pasteur.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102641/ https://www.ncbi.nlm.nih.gov/pubmed/32032682 http://dx.doi.org/10.1016/j.micinf.2020.01.004 |
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author | Chen, Jieliang |
author_facet | Chen, Jieliang |
author_sort | Chen, Jieliang |
collection | PubMed |
description | A zoonotic coronavirus, tentatively labeled as 2019-nCoV by the World Health Organization (WHO), has been identified as the causative agent of the viral pneumonia outbreak in Wuhan, China, at the end of 2019. Although 2019-nCoV can cause a severe respiratory illness like SARS and MERS, evidence from clinics suggested that 2019-nCoV is generally less pathogenic than SARS-CoV, and much less than MERS-CoV. The transmissibility of 2019-nCoV is still debated and needs to be further assessed. To avoid the 2019-nCoV outbreak turning into an epidemic or even a pandemic and to minimize the mortality rate, China activated emergency response procedures, but much remains to be learned about the features of the virus to refine the risk assessment and response. Here, the current knowledge in 2019-nCoV pathogenicity and transmissibility is summarized in comparison with several commonly known emerging viruses, and information urgently needed for a better control of the disease is highlighted. |
format | Online Article Text |
id | pubmed-7102641 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Author(s). Published by Elsevier Masson SAS on behalf of Institut Pasteur. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71026412020-03-31 Pathogenicity and transmissibility of 2019-nCoV—A quick overview and comparison with other emerging viruses Chen, Jieliang Microbes Infect Article A zoonotic coronavirus, tentatively labeled as 2019-nCoV by the World Health Organization (WHO), has been identified as the causative agent of the viral pneumonia outbreak in Wuhan, China, at the end of 2019. Although 2019-nCoV can cause a severe respiratory illness like SARS and MERS, evidence from clinics suggested that 2019-nCoV is generally less pathogenic than SARS-CoV, and much less than MERS-CoV. The transmissibility of 2019-nCoV is still debated and needs to be further assessed. To avoid the 2019-nCoV outbreak turning into an epidemic or even a pandemic and to minimize the mortality rate, China activated emergency response procedures, but much remains to be learned about the features of the virus to refine the risk assessment and response. Here, the current knowledge in 2019-nCoV pathogenicity and transmissibility is summarized in comparison with several commonly known emerging viruses, and information urgently needed for a better control of the disease is highlighted. The Author(s). Published by Elsevier Masson SAS on behalf of Institut Pasteur. 2020-03 2020-02-04 /pmc/articles/PMC7102641/ /pubmed/32032682 http://dx.doi.org/10.1016/j.micinf.2020.01.004 Text en © 2020 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Chen, Jieliang Pathogenicity and transmissibility of 2019-nCoV—A quick overview and comparison with other emerging viruses |
title | Pathogenicity and transmissibility of 2019-nCoV—A quick overview and comparison with other emerging viruses |
title_full | Pathogenicity and transmissibility of 2019-nCoV—A quick overview and comparison with other emerging viruses |
title_fullStr | Pathogenicity and transmissibility of 2019-nCoV—A quick overview and comparison with other emerging viruses |
title_full_unstemmed | Pathogenicity and transmissibility of 2019-nCoV—A quick overview and comparison with other emerging viruses |
title_short | Pathogenicity and transmissibility of 2019-nCoV—A quick overview and comparison with other emerging viruses |
title_sort | pathogenicity and transmissibility of 2019-ncov—a quick overview and comparison with other emerging viruses |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102641/ https://www.ncbi.nlm.nih.gov/pubmed/32032682 http://dx.doi.org/10.1016/j.micinf.2020.01.004 |
work_keys_str_mv | AT chenjieliang pathogenicityandtransmissibilityof2019ncovaquickoverviewandcomparisonwithotheremergingviruses |