Cargando…

Functional effects of variation in transcription factor binding highlight long-range gene regulation by epromoters

Identifying DNA cis-regulatory modules (CRMs) that control the expression of specific genes is crucial for deciphering the logic of transcriptional control. Natural genetic variation can point to the possible gene regulatory function of specific sequences through their allelic associations with gene...

Descripción completa

Detalles Bibliográficos
Autores principales: Mitchelmore, Joanna, Grinberg, Nastasiya F, Wallace, Chris, Spivakov, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102942/
https://www.ncbi.nlm.nih.gov/pubmed/32112106
http://dx.doi.org/10.1093/nar/gkaa123