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Functional effects of variation in transcription factor binding highlight long-range gene regulation by epromoters
Identifying DNA cis-regulatory modules (CRMs) that control the expression of specific genes is crucial for deciphering the logic of transcriptional control. Natural genetic variation can point to the possible gene regulatory function of specific sequences through their allelic associations with gene...
Autores principales: | Mitchelmore, Joanna, Grinberg, Nastasiya F, Wallace, Chris, Spivakov, Mikhail |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102942/ https://www.ncbi.nlm.nih.gov/pubmed/32112106 http://dx.doi.org/10.1093/nar/gkaa123 |
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