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A crucial RNA-binding lysine residue in the Nab3 RRM domain undergoes SET1 and SET3-responsive methylation

The Nrd1–Nab3–Sen1 (NNS) complex integrates molecular cues to direct termination of noncoding transcription in budding yeast. NNS is positively regulated by histone methylation as well as through Nrd1 binding to the initiating form of RNA PolII. These cues collaborate with Nrd1 and Nab3 binding to t...

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Detalles Bibliográficos
Autores principales: Lee, Kwan Yin, Chopra, Anand, Burke, Giovanni L, Chen, Ziyan, Greenblatt, Jack F, Biggar, Kyle K, Meneghini, Marc D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102954/
https://www.ncbi.nlm.nih.gov/pubmed/31960028
http://dx.doi.org/10.1093/nar/gkaa029