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A crucial RNA-binding lysine residue in the Nab3 RRM domain undergoes SET1 and SET3-responsive methylation
The Nrd1–Nab3–Sen1 (NNS) complex integrates molecular cues to direct termination of noncoding transcription in budding yeast. NNS is positively regulated by histone methylation as well as through Nrd1 binding to the initiating form of RNA PolII. These cues collaborate with Nrd1 and Nab3 binding to t...
Autores principales: | Lee, Kwan Yin, Chopra, Anand, Burke, Giovanni L, Chen, Ziyan, Greenblatt, Jack F, Biggar, Kyle K, Meneghini, Marc D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102954/ https://www.ncbi.nlm.nih.gov/pubmed/31960028 http://dx.doi.org/10.1093/nar/gkaa029 |
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