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Poly(ADP-ribosyl)ation mediates early phase histone eviction at DNA lesions
Nucleosomal histones are barriers to the DNA repair process particularly at DNA double-strand breaks (DSBs). However, the molecular mechanism by which these histone barriers are removed from the sites of DNA damage remains elusive. Here, we have generated a single specific inducible DSB in the cells...
Autores principales: | Yang, Guang, Chen, Yibin, Wu, Jiaxue, Chen, Shih-Hsun, Liu, Xiuhua, Singh, Anup Kumar, Yu, Xiaochun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102957/ https://www.ncbi.nlm.nih.gov/pubmed/31965183 http://dx.doi.org/10.1093/nar/gkaa022 |
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