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Cooperation of the NEIL3 and Fanconi anemia/BRCA pathways in interstrand crosslink repair

The NEIL3 DNA glycosylase is a base excision repair enzyme that excises bulky base lesions from DNA. Although NEIL3 has been shown to unhook interstrand crosslinks (ICL) in Xenopus extracts, how NEIL3 participants in ICL repair in human cells and its corporation with the canonical Fanconi anemia (FA...

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Detalles Bibliográficos
Autores principales: Li, Niu, Wang, Jian, Wallace, Susan S, Chen, Jing, Zhou, Jia, D’Andrea, Alan D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102959/
https://www.ncbi.nlm.nih.gov/pubmed/31980815
http://dx.doi.org/10.1093/nar/gkaa038