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Intra-locked G-quadruplex structures formed by irregular DNA G-rich motifs

G-rich DNA sequences with tracts of three or more continuous guanines (G(≥3)) are known to have high propensity to adopt stable G-quadruplex (G4) structures. Bioinformatic analyses suggest high prevalence of G-rich sequences with short G-tracts (G(≤2)) in the human genome. However, due to limited st...

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Detalles Bibliográficos
Autores principales: Maity, Arijit, Winnerdy, Fernaldo Richtia, Chang, Weili Denyse, Chen, Gang, Phan, Anh Tuân
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102960/
https://www.ncbi.nlm.nih.gov/pubmed/32100003
http://dx.doi.org/10.1093/nar/gkaa008