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Molecular basis for t(6)A modification in human mitochondria

N (6)-Threonylcarbamoyladenosine (t(6)A) is a universal tRNA modification essential for translational accuracy and fidelity. In human mitochondria, YrdC synthesises an l-threonylcarbamoyl adenylate (TC-AMP) intermediate, and OSGEPL1 transfers the TC-moiety to five tRNAs, including human mitochondria...

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Detalles Bibliográficos
Autores principales:	Zhou, Jing-Bo, Wang, Yong, Zeng, Qi-Yu, Meng, Shi-Xin, Wang, En-Duo, Zhou, Xiao-Long
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102964/ https://www.ncbi.nlm.nih.gov/pubmed/32047918 http://dx.doi.org/10.1093/nar/gkaa093

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