CDK-Mediator and FBXL19 prime developmental genes for activation by promoting atypical regulatory interactions

Appropriate developmental gene regulation relies on the capacity of gene promoters to integrate inputs from distal regulatory elements, yet how this is achieved remains poorly understood. In embryonic stem cells (ESCs), a subset of silent developmental gene promoters are primed for activation by FBX...

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Detalles Bibliográficos
Autores principales: Feldmann, Angelika, Dimitrova, Emilia, Kenney, Alexander, Lastuvkova, Anna, Klose, Robert J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102981/
https://www.ncbi.nlm.nih.gov/pubmed/31996894
http://dx.doi.org/10.1093/nar/gkaa064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102981/
https://www.ncbi.nlm.nih.gov/pubmed/31996894
http://dx.doi.org/10.1093/nar/gkaa064

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