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CDK-Mediator and FBXL19 prime developmental genes for activation by promoting atypical regulatory interactions
Appropriate developmental gene regulation relies on the capacity of gene promoters to integrate inputs from distal regulatory elements, yet how this is achieved remains poorly understood. In embryonic stem cells (ESCs), a subset of silent developmental gene promoters are primed for activation by FBX...
Autores principales: | Feldmann, Angelika, Dimitrova, Emilia, Kenney, Alexander, Lastuvkova, Anna, Klose, Robert J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102981/ https://www.ncbi.nlm.nih.gov/pubmed/31996894 http://dx.doi.org/10.1093/nar/gkaa064 |
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