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IDR2D identifies reproducible genomic interactions

Chromatin interaction data from protocols such as ChIA-PET, HiChIP and Hi-C provide valuable insights into genome organization and gene regulation, but can include spurious interactions that do not reflect underlying genome biology. We introduce an extension of the Irreproducible Discovery Rate (IDR...

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Detalles Bibliográficos
Autores principales:	Krismer, Konstantin, Guo, Yuchun, Gifford, David K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102997/ https://www.ncbi.nlm.nih.gov/pubmed/32009147 http://dx.doi.org/10.1093/nar/gkaa030

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