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Decitabine: a historical review of the development of an epigenetic drug
The development of decitabine from its synthesis in 1964 to the submission of a registration file has been described. Although the unique DNA-demethylating capacity of decitabine is known for a long time, its application is under continuing investigation. The use of decitabine in MDS, AML, CML, stem...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103145/ https://www.ncbi.nlm.nih.gov/pubmed/16220311 http://dx.doi.org/10.1007/s00277-005-0008-x |