Length of encapsidated cargo impacts stability and structure of in vitro assembled alphavirus core-like particles

In vitro assembly of alphavirus nucleocapsid cores, called core-like particles (CLPs), requires a polyanionic cargo. There are no sequence or structure requirements to encapsidate single-stranded nucleic acid cargo. In this work, we wanted to determine how the length of the cargo impacts the stabili...

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Detalles Bibliográficos
Autores principales: Rayaprolu, Vamseedhar, Moore, Alan, Wang, Joseph Che-Yen, Goh, Boon Chong, Perilla, Juan R, Zlotnick, Adam, Mukhopadhyay, Suchetana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOP Publishing 2017
Materias:
Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103146/
https://www.ncbi.nlm.nih.gov/pubmed/28975896
http://dx.doi.org/10.1088/1361-648X/aa90d0

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