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A 2a/1b full-length p7 inter-genotypic chimeric genome of hepatitis C virus is infectious in vitro

The p7 protein of hepatitis C virus (HCV) functions as an ion channel in planar lipid bilayers, and its function is vital for the virus life cycle. In this study, we replaced either the entire or partial p7 of genotype 2a (strain JFH1), an HCV strain that replicates and produces virus progeny in vit...

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Detalles Bibliográficos
Autores principales: Haqshenas, G., Dong, X., Ewart, G., Bowden, S., Gowans, E.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103279/
https://www.ncbi.nlm.nih.gov/pubmed/17097709
http://dx.doi.org/10.1016/j.virol.2006.10.014