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Lipid-based delivery systems and intestinal lymphatic drug transport: A mechanistic update()
After oral administration, the majority of drug molecules are absorbed across the small intestine and enter the systemic circulation via the portal vein and the liver. For some highly lipophilic drugs (typically log P > 5, lipid solubility > 50 mg/g), however, association with lymph lipoprotei...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier B.V.
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103284/ https://www.ncbi.nlm.nih.gov/pubmed/18155316 http://dx.doi.org/10.1016/j.addr.2007.09.007 |